Research Archives



March 10, 2008

Mechanisms - Knowing and Curing

By answering the question of how diabetes surgery works, we may be answering the question of how diabetes itself works. Gastric bypass surgery can lead to diabetes remission independent of weight loss even in subjects who are are not obese,... ... more

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February 27, 2008

Do you know diabetes research?

Vaccines cause diabetes? Vaccines are Likely to Cause Insulin Dependent Diabetes in Over 2% of Children With a Strong Family History of Insulin Dependent Diabetes. - more More Non-invasive hype? Researchers at Baylor University, in Waco, TX, have engineered a... ... more

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July 6, 2007

Diabetes Fight May Be Helped By New Molecular Target

Researchers say that the fight against diabetes could be helped by targeting a newly discovered molecule, a microRNA known as miR124:The researchers found that miR124 inhibits the production of insulin in the pancreas. It does this by controlling how several... ... more

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July 5, 2007

High Glucose Levels Can 'Lock' body's Metabolism In A Diabetic State

Research has speculated that exposure to high glucose levels quickly creates a metabolic memory in which diabetes persists long after glucose levels have been corrected. Studies to date suggested that oxidation played a role but the exact mechanism was unknown.... ... more

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January 2, 2007

It works in mice ...

We've heard it before, but this is interesting:Chinese scientists say they have identified a molecule that may hold the key to developing new pills to treat diabetes, a growing health concern affecting almost 21 million Americans. The compound, called Boc5,... ... more

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April 21, 2006

New Plan May Reverse Type 1 Diabetes - at least in mice

Strong synergy is the key- combining a vaccine and an immunosuppressant drug:Scientists have used a two-pronged treatment to reverse recent-onset type 1 diabetesdiabetes in mice. The approach hasn't yet been tested on humans, but the results from tests on mice... ... more

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March 7, 2006

Researchers Relate Mitochondria Activity to Type 2 Diabetes

Insulin resistance, the predecessor to Type 2 Diabetes, relates to the ineffectiveness of the insulin hormone to transfer glucose into the body's cells to be used as fuel. In particular, insulin binds to a spot on the cell surface called... ... more

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July 22, 2005

Study Identifies Fat-Secreted Protein Linked To Insulin Resistance

A study led by researchers at Beth Israel Deaconess Medical Center (BIDMC) has shown that a protein found in fat cells is a newly discovered cause of insulin resistance, establishing a previously unidentified molecular link between obesity and type 2... ... more

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June 14, 2005

Type 1 Diabetics have Beta Cells

In type 1 diabetes, which by definition indicates a lack of insulin production, the insulin-producing "beta" cells in the pancreas are thought to be wiped out. At least, this was the common understanding until a new study provided evidence that... ... more

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May 27, 2005

Antibiotic Minocycline May Prevent Blindness

NEW YORK (Reuters Health) - Experiments in rats suggest that minocycline, an antibiotic, could curb a common cause of vision problems in people with diabetes. Minocycline is a "strong candidate for further consideration as a therapeutic drug in reducing the... ... more

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May 23, 2005

Joslin Diabetes Center Scientists Find 'Brown Fat Cells' Hold Clues for Possible Obesity Treatments

BOSTON--(BUSINESS WIRE)--May 23, 2005--Joslin Diabetes Center scientists have discovered a group of genes that govern the genesis of calorie-burning fat cells. This discovery may lead to novel ways to treat obesity in humans. "With obesity at epidemic levels, finding new... ... more

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May 20, 2005

Good news on diabetes research - early but promising

From NewHopeBlog: Results of a recent study offer new hope for novel treatment options in diabetes. Scientists have successfully modified liver cells to produce insulin that, when transplanted into mice, brought diabetes under control.... ... more

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May 17, 2005

Excess Body Fat Can Lead to the Onset of Diabetes

Scientists at the Weizmann Institute of Science, Israel, and in Sweden Discover How Excess Body Fat Can Lead to the Onset of Diabetes

... more

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May 13, 2005

What Causes Type I Diabetes?

NewHopeBlog has published more information related to a report about the mechanisms leading to Type I diabetes:The results of long-term studies indicate that insulin is the trigger that unleashes autoimmune lymphocytes to attack beta islet cells in the pancreas that... ... more

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May 11, 2005

Researchers Uncover Mechanisms Leading to Type I Diabetes

Researchers believe they have made an important breakthrough in understanding the severest form of diabetes, confirming that the disease begins when the body's immune system reacts to the hormone insulin. Type 1 diabetes usually occurs in childhood, when immune cells... ... more

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May 4, 2005

Optimal Insulin Pump Dosing and Postprandial Glycemia Following a Pizza Meal Using the Continuous Glucose Monitoring System

The "pizza" study was published in the April issue of Diabetes Technology & Therapeutics and is the first clinical examination of the optimal timing of the dual-wave administration of insulin... I'm sure recruitment was not a problem. The general conclusions... ... more

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April 25, 2005

Breaking News - Brain Stem Cells May Treat Diabetes

Following ground-breaking research, US scientists believe they have found a way to use brain stem cells to "cure" diabetes. Although the work is not yet ready to be tested on human patients, results in animals have been promising, say the... ... more

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Another Transplate Success

An islet cell transplant performed at Carolinas Medical Center in Charlotte, NC appears to have had success after three procedures:Andrea Anderson is a transplant recipient, "It's still hard to believe I'm off insulin, when I do tests with my meter,... ... more

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April 23, 2005

Propensity for Obesity, Diabetes May Occur In Utero

A study conducted at the University of Buffalo (on rats) indicates that obesity and diabetes may be influenced by the maternal intrauterine environment. The researchers believe (of course) that their results can be extended to humans. The adage "You are... ... more

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April 22, 2005

Update on the Recent Islet Cell Transplant

All eyes are on the recipient of the first transplant of the insulin producing islet cells from a live donor. A healthy 56-year-old woman without diabetes donated half of her pancreas to her 27-year-old daughter in a ground breaking procudure.... ... more

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Spleen Stem Cells Produce Potential Cures

Previously, researchers discovered that adult stem cells taken from the spleen could regenerate the insulin-producing islets of the pancreas. The finding is significant because it provides a potential cure for diabetes. The same team is now reporting that spleen adult... ... more

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April 19, 2005

Diabetes and Stem Cell Research

Type I diabetes, commonly diagnosed during childhood, is a condition in which the body does not produce insulin. Insulin is a hormone that is used in the body to process glucose by transporting it from blood into cells. Consequently, the... ... more

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